Description
What is Lucifutib 4 mg used for?
Lucifutib 4 mg is a brand of Futibatinib, a targeted FGFR (fibroblast growth factor receptor) inhibitor used to treat adults with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma (a type of bile duct cancer) that carries FGFR2 gene fusions or other rearrangements. It works by blocking abnormal FGFR signals that tell cancer cells to grow. The usual dose is 20 mg (five 4 mg tablets) once a day, taken until the disease progresses or side effects become unacceptable. Futibatinib is a prescription-only medicine taken under the care of a cancer specialist.
Key Facts
| Detail | Information |
|---|---|
| Brand name | Lucifutib 4 mg |
| Generic / active ingredient | Futibatinib 4 mg |
| Drug class | FGFR1–4 inhibitor (targeted kinase inhibitor) |
| Dosage form | Film-coated oral tablet |
| Strength | 4 mg per tablet |
| Primary use | Previously treated, advanced FGFR2+ intrahepatic cholangiocarcinoma (bile duct cancer) in adults |
| Usual dose | 20 mg (five 4 mg tablets) once daily |
| How to take | Swallow whole, once daily — do not crush, chew or split |
| Originator brand | Lytgobi® (Taiho Oncology) |
| Prescription status | Prescription only (Rx) |
| Storage | Store at room temperature, in original pack, away from moisture & children |
How Lucifutib Works
Some bile duct cancers grow because of a faulty gene called FGFR2, which sends out constant “grow” signals through a receptor called FGFR.
Futibatinib — the active ingredient in Lucifutib — is a targeted FGFR inhibitor. It locks onto the FGFR receptor and switches off those abnormal growth signals, helping to slow or stop the cancer’s growth.
In one line: Lucifutib blocks the faulty FGFR signal that drives FGFR2+ bile duct cancer to grow.
Uses
- Intrahepatic cholangiocarcinoma (bile duct cancer) — in adults with unresectable, locally advanced or metastatic disease that has FGFR2 gene fusions or other rearrangements, and that has already been treated with at least one prior therapy.
Dosage & How to Take
- Usual dose: 20 mg — five 4 mg tablets — taken once a day, with or without food.
- Take it at about the same time each day. Swallow tablets whole — do not crush, chew, split or dissolve them.
- Keep taking it daily until your doctor advises otherwise (usually until the disease progresses or side effects need a change).
- If side effects occur, your doctor may lower the dose (to 16 mg, then 12 mg) or pause treatment. Never change the dose yourself.
- If you miss a dose or vomit after taking it, do not take an extra dose — just take the next dose at the usual time.
Side Effects
Very common: high phosphate levels in the blood (hyperphosphatemia), nail changes, dry mouth, fatigue, constipation, diarrhoea, muscle and joint pain, mouth sores (stomatitis), and hand-foot syndrome (redness/soreness of palms and soles).
Serious — contact your care team promptly: changes in vision or eye problems (including retinal disorders), signs of liver problems, or very high phosphate levels. Your doctor will monitor blood phosphate and eyes during treatment.
Warnings & Precautions
- Hyperphosphatemia is common — your doctor will check blood phosphate regularly and may advise a low-phosphate diet, phosphate-lowering medicine, or a dose change.
- Eye (retinal) disorders can occur — report any vision changes; regular eye exams are recommended.
- Do not use during pregnancy — Futibatinib can harm an unborn baby. Both men and women should use effective contraception during treatment and for a period after stopping, as advised by the doctor.
- Do not breastfeed during treatment and for a short time afterwards.
- Tell your doctor about all other medicines you take, as some can interact with Futibatinib.
Storage
Store at room temperature in the original package, away from moisture. Keep out of the sight and reach of children. Do not use after the expiry date on the pack.
FAQ
What is Lucifutib 4 mg?
Lucifutib 4 mg is a brand of Futibatinib, a targeted FGFR inhibitor used to treat adults with previously treated, advanced bile duct cancer (intrahepatic cholangiocarcinoma) that has FGFR2 gene fusions or rearrangements.
What is the generic name of Lucifutib?
The generic name (active ingredient) is Futibatinib. The internationally known originator brand is Lytgobi®.
How do I take Lucifutib 4 mg?
The usual dose is 20 mg — five 4 mg tablets — once a day. Swallow the tablets whole with water; do not crush or chew them. Always follow your oncologist’s instructions.
Is Lucifutib chemotherapy?
No. Lucifutib is a targeted therapy, not traditional chemotherapy. It blocks a specific cancer driver (FGFR) rather than attacking all fast-dividing cells.
What are the main side effects of Lucifutib?
The most common is high blood phosphate (hyperphosphatemia). Others include nail changes, dry mouth, tiredness, mouth sores, hand-foot syndrome, and digestive changes. Eye and liver problems can also occur and are monitored.
Do I need a prescription to buy Lucifutib 4 mg?
Yes. Lucifutib is a prescription-only (Rx) cancer medicine and must be taken under the supervision of an oncologist.
Can I take Lucifutib during pregnancy?
No. Futibatinib can harm an unborn baby. Effective contraception is required during treatment and for a period afterwards, as advised by your doctor.
Medical Disclaimer
This information is for general educational purposes only and is not a substitute for professional medical advice. Lucifutib (Futibatinib) is a prescription-only anti-cancer medicine. Always consult a qualified oncologist or pharmacist before starting, stopping or changing treatment. Do not self-medicate.
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