Description
LuciAbro 100mg is an oral tablet containing Abrocitinib 100 mg, manufactured by Lucius Pharmaceuticals Ltd., Bangladesh. It is a once-daily, selective Janus kinase 1 (JAK1) inhibitor prescribed for moderate-to-severe atopic dermatitis (eczema) in adults and adolescents aged 12 and older whose condition is not controlled by topical treatments or biologics.
LuciAbro contains the same active ingredient as Cibinqo (Pfizer), which received US FDA approval in January 2022.
How LuciAbro 100mg Works
Abrocitinib selectively blocks the JAK1 enzyme, interrupting inflammatory cytokine signals (IL-4, IL-13, IL-31, IL-22, and TSLP) that drive eczema. This reduces itching, redness, and skin inflammation — often within the first week of treatment. Read more about abrocitinib’s mechanism on DermNet NZ.
Uses
LuciAbro 100mg is prescribed for patients with moderate-to-severe atopic dermatitis when:
- Topical corticosteroids no longer control flare-ups
- Other systemic therapies or biologics (e.g., dupilumab) have failed or are unsuitable
- Persistent itch, rash, or sleep disturbance affects daily life
Can be used as monotherapy or with topical corticosteroids. Learn more about atopic dermatitis from the National Eczema Association.
Dosage
| Detail | Information |
|---|---|
| Standard dose | 100 mg once daily |
| Maximum dose | 200 mg once daily (if 100 mg is insufficient after 12 weeks) |
| With food | Yes or no — food does not affect absorption |
| Administration | Swallow whole with water; do not crush or chew |
| Onset of itch relief | 2–4 days |
| Full skin improvement | 12–16 weeks |
Follow your doctor’s prescription. Full prescribing information is available in the official FDA label for Cibinqo (abrocitinib). Storage: keep below 30°C, away from light and moisture.
Product Specifications
- Active Ingredient: Abrocitinib USP 100 mg
- Drug Class: Selective JAK1 Inhibitor
- Manufacturer: Lucius Pharmaceuticals Ltd., Bangladesh
- Reference Brand: Cibinqo® (Pfizer)
- Form: Film-coated oral tablet
Side Effects
Common: nausea, headache, acne, nasopharyngitis (cold symptoms), herpes simplex.
Serious: (seek medical help): serious infections, blood clots, low blood cell counts, cardiovascular events.
Baseline tests (CBC, liver function, TB screening) are required before starting. Avoid during pregnancy or breastfeeding. Use caution in patients over 65, smokers, or those with a history of clots or infection.
FAQ
What is LuciAbro 100mg used for?
LuciAbro 100mg is used to treat moderate-to-severe atopic dermatitis (eczema) in patients aged 12 and older when topical or other systemic treatments have failed.
Is LuciAbro the same as Cibinqo?
Yes. Both contain Abrocitinib as the active ingredient. LuciAbro is the Lucius Pharmaceuticals (Bangladesh) version.
How quickly does Abrocitinib work?
Itch relief often begins within 2–4 days. Significant skin improvement usually occurs within 12 weeks.
Can I take it with food?
Yes — with or without food. Take it at the same time daily.
What’s the difference between 100mg and 200mg?
100 mg is the standard starting dose. 200 mg is used if 100 mg is not effective enough after 12 weeks. Your doctor decides.
Is it safe during pregnancy?
No. Abrocitinib is not recommended during pregnancy or breastfeeding. Use contraception during and for one month after treatment.
How should it be stored?
Below 30°C, in a cool, dry place away from sunlight and out of reach of children.
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